Institut Charles Gerhardt
Equipe Architectures Moléculaires et Matériaux Nanostructurés
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Gilles NIEL’s own page

Research Assistant at ENSCMontpellier

ICG Montpellier UMR 5253 / AM2N team

ENSCM, 8 rue de l’Ecole Normale 34296 Montpellier Cedex 5

Tel : +33.467 14 43 37 E-mail : gilles.niel@enscm.fr


Research themes

  • 1983-1992 - synthesis of leukotriene analogs related to antiasthma drugs
  • 1992-2001 - methodology about modified aminoacid synthesis and application to the total synthesis of peptides and cyclodepsipeptides possessing potent cytotoxic activities.
  • 2001-2008 - design of chemical information systems - information modelling related to chemical reasoning.
  • 2009-2011 - total synthesis of thuggacin A.
  • 2011- Indexing in bibliographic databases

Curriculum vitae

  • 2009 - Integration in Pr. J-M. Campagne’s lab (UMR5253-ICGM)
  • 2001 - Integration in Dr. C. Laurenço’s team (UMR5076)
  • 1992 - Integration in Dr. P. Jouin’s lab (now UMR 5203)
  • 1989 - post-doctoral stage in Pr. R. W. Hoffmann’s lab – Fachbereich Chemie der Philipps-Universität - Marburg (FRG).
  • 1985 - Admission to the CNRS as Chargé de Recherches in Pr.J. C. Rossi’s lab (URA 1111)
  • 1983 - Research Engineer in Pr.J. C. Rossi’s lab (URA 1111) - Montpellier

Recent publications

  • Graph-Mining Algorithm for the Evaluation of Bond Formability. Pennerath F., Niel G., Vismara P., Jauffret P., Lauren C., Napoli A. Journal of Chemical Information and Modeling¸ 2010, 50 (2) 221-239
  • Towards the Total Synthesis of Thuggacin A: Synthesis of the C13-C25 Fragment Bearing All-syn Stereocenters. Zarate-Ruiz A., Marcia De Figueiredo R., Niel G., Campagne J.-M. Synlett, 2011, 23(2), 219-222
  • Update 1 of : Macrolactonizations in the total synthesis of natural products. Parenty A., Moreau X., Niel G., Campagne J.-M Chemical Reviews, 2013, 113(1), PR1-40.
FULL LIST
PDF - 138.7 kb

Teaching

Course about the use of chemical information sources in particular through learning Chemical Abstracts Service (CAS) and Reaxys databases. The web interfaces of both editors are detailed in order to highlight their abilities to answer queries by :

  • keywords (authors, titles, abstracts ...) with perfect control of the indexing policies and of boolean operators.
  • structure and substructure about substances and reactions.

The access to full-text articles, therefore to available electronic documentation, is described.


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